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NFL PREDICTION, CARDINALS VS COLTS! 10/12/2025

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Michael Pittman Jr. Anytime Touchdown (+165) 

 Pittman has been the Colts’ most reliable red-zone target, and in a matchup against a struggling Cardinals secondary that ranks near the bottom of the league in explosive pass plays allowed, his touchdown upside is strong. He’s averaged over eight targets per game and remains the clear first read for Gardner Minshew in scoring territory. With Arizona’s defense often blitzing and leaving one-on-one coverage on the outside, Pittman’s physicality gives him a clear advantage on fades and slants inside the 10-yard line. At +165, the odds present solid value for a player projected to see double-digit targets and multiple red-zone looks, making this a calculated play with high-reward potential.


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